Cannabidiol (CBD) Oil; The FACTS
Although it is controversial, Cannabidiol oil is used for therapeutic purposes. There may be some confusion about the nature of CBD oil and the effects it produces on the body.
Cannabidiol (CBD) is considered one of many compounds, called cannabinoids, which are found in the cannabis plant. Researchers have started looking at the potential therapeutic benefits of CBD use. CBD has a lot of therapeutic uses. However, there may also be a few risk associated with it and so it is not legal in every state.
Oils that comprise concentrations of CBD are referred to as CBD oils. The concentration and uses of various CBD oils vary. Many people are constantly searching the web for an explanation for what CBD is, what it can be used for, its associated risks, the legality of CBD, and the way to use it.
CBD as a constituent in Cannabis
Until recently, the most popular compound in cannabis was delta-9 tetrahydrocannabinol (THC) which is the most active chemical compound in cannabis. It is well established now that Cannabis contains both THC and CBD, but the compounds have distinct effects.
THC is well-known for the psychoactive “high” feeling it produces when consumed into the body usually damaged down by heat such as while smoking the plant or cooking it into ingredients.
However, CBD is not psychoactive like THC. It literally does not affect the state of mind or thoughts of the individual that consumes it. Although, it also produces significant changes in the body and has been discovered to have therapeutic uses.
Most of the CBD used therapeutically is found in the least processed form of the cannabis plant, referred to as hemp. Hemp and marijuana both come from the same Cannabis sativa plant, however, there are some marked differences.
Over time, marijuana farmers have selectively bred their plant to be very high in THC and other compounds of interest, either for a smell or an effect it produces on the plant’s flowers.
Alternatively, hemp farmers have not seemed to tend to alter the plant. These hemp plants have been greatly used to produce CBD oil.
Mechanism of action of CBD Oil
All cannabinoids, including CBD bind to specific cannabinoid receptors in the body to produce their effects. The human body also produces its own cannabinoids known as endocannabinoids e.g. anandamide. There are basically two cannabinoids receptors for cannabinoids, known as CB1 receptors and CB2 receptors.
CB1 receptors are mainly localized in the brain but can be found in other parts of the body. The CB1 receptors in the brain are involved with coordination and motion, pain, emotion, thoughts, memories, and appetite, amongst others. THC attaches to these CB1 receptors.
CB2 receptors usually found in the immune system and associated organs like spleen and thymus glands. They are usually involved in inflammation and pain.
It was usually believed that CBD acts on those CB2 receptors, however, it appears now that CBD does not act on both receptors directly. Instead, it appears to stimulate the body to use more of its own cannabinoids.
Benefits of CBD Oil
Due to the manner by which CBD oil acts in the body, it has many therapeutic uses.
- Pain relief and anti-inflammatory properties: Individuals generally use prescription or over-the-counter drugs to alleviate pain and stiffness, including chronic pain. Some individuals are of the opinion that CBD oil offers a greater natural remedy to reduce pain. A research published in the Journal of Experimental Medicine discovered that CBD oil substantially reduced chronic inflammation and pain in a few mice and rats. The researchers endorse that the non-psychoactive compounds in marijuana, such as CBD oil, could serve as a new treatment for chronic pain.
- Drug withdrawals and quitting smoking: There is some promising evidence that CBD oil use in the body can also individuals to quit smoking. A pilot study published on Addictive Behaviors found that smokers who used an inhaler containing the compound CBD oil smoked fewer cigarettes, however, did no longer have any extra longing for nicotine. A similar study published on Neurotherapeutics found that CBD oil can be a promising substance for individuals who abuse opioids. Researchers noticed that a few signs and symptoms experienced with patients with substance use disorders are probably decreased through CBD oil. These disorders include anxiety, pain, mood symptoms, and insomnia. These early findings suggest that CBD oil may be used to avoid or lessen withdrawal symptoms.
- Epilepsy and neuropsychiatric disorders: CBD oil is likewise being studied for its feasible function in treating epilepsy and other mental health disorders. A study posted by Epilepsia noticed that CBD oil has anti-seizure properties and low associated side effects for patients with epilepsy. Research into CBD oil’s effect on neurological disorders recommends that it can help to treat the various disorders which can be related to epilepsy, including neurodegeneration, neuronal damage, and psychiatric sicknesses. A similar study posted in Current Pharmaceutical Design found that CBD oil may additionally have similar consequences to certain antipsychotic medications and that it is effective and safe in treating people suffering from schizophrenia. However, more study needs to be done to fully understand this mechanism.
- Cancers: CBD oil has been studied for its use as an anti-cancer agent. A research posted to the British Journal of Clinical Pharmacology found that CBD oil appears to reduce the metastasis of most cancers cells from spreading across the body and invading an entirely new. The research indicates that this CBD Oil tends to suppress the growth of cancer cells and also promote the death of these cancer cells. Researchers noticed that CBD oil may additionally assist in most cancers treatment due to its low toxicity degrees. Researchers are calling for it to be studied in conjunction with standard treatment to check for s any possibility of synergistic effects.
- Anxiety disorders: Until recently, patients suffering from chronic anxiety are usually advised to avoid cannabis, as THC can trigger or amplify anxiety and paranoia in some individuals. However, a research carried out by Neurotherapeutics shows that CBD oil may additionally help to reduce the anxiety felt by individuals with certain anxiety disorders. The research findings showed that the use of CBD oil may also reduce anxiety behaviors in issues such as post-traumatic stress disorder, general anxiety disorder, and social and panic anxiety disorder. The researchers noticed that present-day medications for these conditions can lead to additional symptoms and side effects. This side effects may stop individuals from taking the medication because of the undesirable effects. CBD oil has not shown any side effects or unfavorable outcomes to date. Therefore, researchers have called for CBD Oil to be studied as a potential alternative for treatment.
- Diabetes Mellitus: Type 1 diabetes is usually caused by inflammation of the pancreas by the immune system. Recent studies posted to Clinical Hemorheology and Microcirculation found that CBD oil may ease the inflammation within the pancreas. This could prove to be the first step in finding a CBD-based treatment for diabetes.
- Acne: CBD oil has been found to have a promising treatment for acne. Acne is caused in part by inflammation and overworked sebaceous glands within the body. A current study published in the Journal of Clinical Investigation discovered that CBD oil helps in lowering the production of sebum that leads to acne, partially due to its anti-inflammatory effect on the body.
- Alzheimer’s disease: A research published in the Journal of Alzheimer’s Disease discovered that CBD oil is able to prevent the development of social recognition deficit in patients. It implies that CBD oil could potentially save patients in the early stages of Alzheimer’s disease from losing their ability to recognize the faces of people they know. This is the first evidence that CBD oil is potentially used to prevent Alzheimer’s disease signs and symptoms.
Legality of CBD Oil
In some states, cannabis is legal for recreational and medicinal uses. Other states approve CBD oil as a hemp product without totally approving the overall use of medical marijuana.
There are many ever-changing numbers of states that do not consider marijuana to be legal but have legal guidelines relating to CBD oil. The laws vary, but they commonly legally approve CBD oil for treating a number of health conditions.
Different states additionally permit different degrees of prescription to own and use CBD oil. In case you are considering CBD oil as a treatment for a health condition, discuss with your local healthcare provider. They will have a knowledge of safe CBD oil sources and laws surrounding usage.
How to use CBD oil
CBD oil is used in special ways to alleviate the symptoms of different conditions.
Some CBD oil products may be combined into specific meals or beverages, taken from a pipette or dropper. CBD oil can also be purchased in capsule form or available as a paste to be massaged into the skin. Other CBD oil products are supplied as sprays which might be meant for administration underneath the tongue.
Below are some recommendable dosages of CBD oil, although these doses may vary among individuals primarily based on other factors. These factors could be body weight, the concentration of the product, and the type of condition being treated.
All dosages relate to taking CBD oil by the oral route. These include:
- Chronic pain: Take about 2.5 to 20 milligrams (mg) by mouth for less than 25 days.
- Epilepsy: Consume about 200 and 300 mg of CBD oil products orally, daily for as much as four to five months.
- Huntington’s disease: For the movement problems associated with this condition. Consumption of 10 mg of CBD oil capsule daily for six weeks can help ease movements.
- Sleep disorders: Consume about 40 to 160 mg.
- Schizophrenia: Take between 40 and 1,280 mg CBD oil product orally, daily for as much as four weeks.
- Glaucoma: One dose of about 20 and less than 40 mg administered underneath the tongue can assist to alleviate the associated pressure in the eye. However, caution is recommended at doses more than 40 mg may increase pressure in the eyes.
Side effects of CBD Oil
Many small-scale studies have looked into the safety of CBD oils in an adult. This studies observed that it is well tolerated across a wide range of doses. There has been some significant side effect of CBD oil in the central nervous system. Also, CBD oil doesn’t have effects on mood and vital signs of individuals who consume CBD oil appropriately. The most common side effects associated with CBD oil is tiredness. Diarrhoea and changes in weight and appetite have been noticed in some people.
Nevertheless, there are little or no long-time safety data available. Thus far, test on CBD oil has not been carried out on children.
As of date, the United States Food and Drug Administration (FDA) has not approved CBD oil for the treatment of any condition. Therefore, it could be hard to recognize whether or not a product contains a safe or effective level of CBD or whether or not the product has the properties and contents as stated on its packaging and advertising.
However, due to the lack of FDA regulation for CBD oil products, seeking advice from a medical expert earlier than deciding on any specific dosage is advisable. As law within the U.S. increases, extra specific doses and prescriptions of CBD oil will start to emerge.
After discussing dosage and associated risks with a physician, and researching nearby legal use, it is important to evaluate different brands with their different benefits and applications.